The Pharmaceutical and Biotech industries consider a number of factors to determine the best diaphragm solution for a given process or application. 

Key factors include:
• Regulatory Compliance
• FDA
• USP 28
• 3A
• Biocompatability
• Material extractibles
• Application temperatures
• Cleaning in place
• Steaming in place
• Passivation
• Failure mode

Applications within the Biotech industry are particularly sensitive to diaphragm materials because of the fact that many of the processes within the industry utilize living organisms. A balance or compromise must be struck between all of the key factors listed. Regulatory compliance in most cases is not sufficient by itself to guarantee a properly functioning system.

The worldwide network of ITT Pure-Flo technical resources are available to assist in determining the proper diaphragm for your application.